Spotlight on: Paediatrics

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Paediatrics

Paediatric clinical trials present unique statistical challenges due to small, heterogeneous populations and ethical constraints. Innovative methodologies like Bayesian statistics are often employed to manage small sample sizes and leverage prior information. The focus is on designing robust trials that ethically generate reliable, paediatric-specific data for dose-finding and efficacy, balancing evidence with the protection of a vulnerable population.



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